THE ACTIVE COMPOUNDS IN POLYSCIAS SCUTELLARIA IDENTIFIED BASED ON THE SOLVENT

Abstract

Polyscias scutellaria, commonly known as bowl leaf, is a medicinal plant belonging to the Araliaceae family, celebrated for its diverse therapeutic properties, particularly in Southeast Asia. This study aimed to explore the phytochemical composition and antioxidant potential of various extracts of Polyscias scutellaria. The active compounds were identified through qualitative and quantitative analyses, employing extraction methods including 96% ethanol, ethyl acetate, and methanol. The phytochemical screening revealed a rich profile of bioactive compounds, including phenolics, flavonoids, saponins, and alkaloids. Notably, the 96% ethanol extract exhibited a phenolic content of 14.67 ± 0.33 mg GAE/g and a flavonoid content of 1.83 ± 0.05 mg QE/g, highlighting its potential as a natural antioxidant source. The ethyl acetate extract displayed the highest total phenolic content of 289.813 ± 11.381 mg GAE/g, indicating its efficiency in extracting valuable compounds. Antioxidant activity assessed via the DPPH method demonstrated significant scavenging effects, with the ethanol extract modern health practices. showing an IC50 value of 46.28 mg/mL, surpassing the n-hexane extract. Additionally, the methanol extract revealed a higher concentration of alkaloids, carbohydrates, and saponins, suggesting its potential for functional health applications. These findings underscore the pharmacological significance of Polyscias scutellariaand its bioactive constituents, emphasizing the need for further research to validate its therapeutic efficacy and explore its applications in drug discovery. Overall, this study contributes to the growing body of evidence supporting the medicinal value of Polyscias scutellaria, advocating for its integration into traditional and